Japanese scientists research: Some mutations increase risk 1.4 times

Japanese scientists research: Some mutations increase risk 1.4 times

In the Covid-19 epidemic, which infects approximately 160 million people worldwide and caused more than 3.33 million deaths, the concern for mutation continues to occupy the agenda of the world public opinion.

A study by a group of researchers from the Japan National Institute of Infectious Diseases found that the different variants that make up the majority of cases in the country are 1.4 times more likely to cause severe symptoms than normal.

In the 3-month period up to May 6, experts examining the data of more than 207 thousand people who tested positive for Covid-19 in Japan, confirmed through PCR test or genome analysis that more than 15 thousand of them were infected with variants carrying the N501Y mutation.

Analyzing the condition of patients infected with corona virus variants carrying the mutation, scientists found that 475 of the individuals developed severe symptoms, including severe pneumonia or multiple organ failure.

People infected with variants carrying the N501Y mutation had a 40 percent higher risk of developing serious symptoms compared to those who were previously infected, while the risk was 66 percent higher than normal in patients aged 40 to 64.


Reminding that it is difficult to fully analyze the risk of Covid-19’s different mutations due to the lack of available data, experts warned that epidemic measures and virus treatment should be carried out based on the assumption that mutations have a higher risk of causing serious symptoms.


It was previously reported that all variants of Covid-19 in England, South Africa, Brazil and India experienced changes in the spike proteins that bind the virus to human cells, and the mutation named N501Y seen in some of them was stated to strengthen the virus in transmitting and spreading to other cells.

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